Souds like the GPU is overheating. Japanese Seawater may help. but will damage your computer beyond repair. If your PC has not much space inside, try removing the cover and see if cooling improves.
Japanese Seawater only works on Nuclear reactor Cores, and unless its powered by that, i think it'll be useless (unless you consider it to be useful to short circuit and erode your computer)
also, try cleaning, dust always makes things overheat, try adding more fans, and like gandalf said, try removing covers