Microsoft security essential or norton are best
Please tell me this is a joke.
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Norton is amazing, yet firewall settings can be tricky at first. Better than MSE.
McAfee isn't free, sucks. It has poor update quality and uses excessive amount of processes. Equal to MSE.
AVG is fairly well. Free Version + trial of premium (1 month). Very customizable. Better than MSE.
KasperSpy, used once for about a week. No problems or complaints, a bit disappointed in the update freqency but again was only a week. Rated higher that MSE (can't be sure).
Bitdefender, as above hardly used can't really give feedback.
Avast, #1 rated free (based on a few sources). Amazing program, no complaints, very adaptable and easy to use. Better than MSE.
SpyBot S&D, worse than MSE, not recommended.
MalwareBytes is a good tool, I will admit this.
MSE(Microsoft Security Essentials) is utterly useless. Sure its a virus scanner, but its lack of frequency in updates, lack of adaptability, customization and over all user-friendly system is what kills it. I personally have tested this on a virtual environment to see what viruses I can download and get passed it (as I do with everyone AV I've used for extended periods of time) and it was quite depressing the results. Common Trojans and backdoors went undetected with only minor "masking" on them. Needless to say, this will never be on my system.
Luckily, I've been on my Linux boot and haven't had any worrying about which anti-virus to use for it, as it isn't required.