Well, I will say my opinion as I'm playing football since 8.
I prefer shoes that I 'feel', which means that when your get hit in the shoes, you don't feel a lot of damage. Therefore, I choose Nike Mercurial. I'm going to post a picture of mine. Being comfort inside is a good option to choose comfortable shoes but imagine Pepe hitting my damn nail while I use Adizero. Seriously..
It is only an example, as I never had a match against Pepe. 
Well you got other things to protect yourself, and you can really do it with shoes, only if somebody with 90kg stands on your foot.

Also you have to choose not to be too heavy for running in them, well it depends on your position.
Since I'm playing side back I have to choose comfort and the ones that don't weight much, and don't get too much water in it, also lasting a long time.
These lasted 1 year for me. But the last two months I felt like shit wearing them.
I would like to avoid Pepe if possible.
